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All chapters rigorously updated with the latest drug information NEW front section clearly explains how the book should be used, including names & displays of logos of key teaching features Increased number of high-yield figures & tables (for instance, to delineate differences between similar drugs), plus more explicit introductions to the chapter material to guide high-yield study Each chapter includes a series of 15-20 relevant USMLE-style questions and ends with a summary of the key drugs 2 USMLE-style Practice Exams with 120 questions each, revised to reflect the USMLE testing experience more closely About the Author : Anthony J. Trevor, PhD , is Professor Emeritus of Pharmacology and Toxicology Department of Cellular and Molecular Pharmacology University of California, San Francisco San Francisco, CA Bertram G. Katzung, MD, PhD, is Professor Emeritus of Pharmacology Department of Cellular and Molecular Pharmacology University of California, San Francisco San Francisco, CA Susan B. Masters, PhD, is Professor and Academy Chair of Pharmacology Education Department of Cellular and Molecular Pharmacology University of California, San Francisco San Francisco, CA Table of Content : Preface I. Basic Principles 1. Introduction 2. Pharmacodynamics 3. Pharmacokinetics 4. Drug Metabolism 5. Drug Evaluation & Regulation II. Autonomic Drugs 6. Introduction to Autonomic Pharmacology 7. Cholinoceptor-Activating & Cholinesterase-Inhibiting Drugs 8. Cholinoceptor Blockers & Cholinesterase Regenerators 9. Sympathomimetics 10. Adrenoceptor Blockers III. Cardiovascular Drugs 11. Drugs Used in Hypertension 12. Drugs Used in tihe Treatment of Angina Pectoris 13. Drugs Used in Heart Failure 14. Antiarrhythmic Drugs 15. Diuretic Agents IV. Drugs with Important Actions on Smooth Muscle 16. Histamine, Serotonin, & the Ergot Alkaloids 17. Vasoactive Peptides 18. Prostaglandins & Other Eicosanoids 19. Nitric Oxide, Donors, and Inhibitors 20. Bronchodilators & Other Drugs Used in Asthma V. Drugs That Act in the Central Nervous System 21. Introduction to CNS Pharmacology 22. Sedative-Hypnotic Drugs 23. Alcohols 24. Antiseizure Drugs 25. General Anesthetics 26. Local Anesthetics 27. Skeletal Muscle Relaxants 28. Drugs Used in Parkinsonism & Other Movement Disorders 29. Antipsychotic Drugs & Lithium 30. Antidepressants 31. Opioid Analgesics & Antagonists 32. Drugs of Abuse VI. Drugs with Important Actions on Blood, Inflammation, & Gout 33. Agents Used in Anemias & Hematopoietic Growth Factors 34. Drugs Used in Coagulation Disorders 35. Drugs Used in the Treatment of Hyperlipidemias 36. NSAIDs, Acetaminophen, & Drugs Used in Rheumatoid Arthritus and Gout VII. Endocrine Drugs 37. Hypothalamic & Pituitary Hormones 38. Thyroid & Antithyroid Drugs 39. Corticosteroids & Antagonists 40. Gonadal Hormones & Inhibitors 41. Pancreatic Hormones, Antidiabetic Agents, & Glucagon 42. Drugs that Affect Bone Mineral Homeostasis VIII. Chemotherapeutic Drugs 43. Beta-Lactam Antibiotics & Other Cell Wall Synthesis Inhibitors 44. Chloramphenicol, Tetracyclines, Macrolides, Clindamycin, Streptogramins, & Linezoid 45. Aminoglycosides 46. Sulfonamides, Trimethoprim, & Fluoroquinolones 47. Antimycobacterial Drugs 48. Antifungal Agents 49. Antiviral Chemotherapy & Prophylaxis 50. Miscellaneous Antimicrobial Agents & Urinary Antiseptics 51. Clinical Use of Antimicrobials 52. Basic Principles of Antiparasitic Chemotherapy 53. Antiprotozoal Drugs 54. Anthelmintic Drugs 55. Cancer Chemotherapy 56. Immunopharmacology IX. Toxicology 57. Environmental and Occupational Toxicology 58. Heavy Metals 59. Management of the Poisoned Patient X. Special Topics 60. Drugs Used in Gastrointestinal Disorders 61. Botanical Medications and Nutritional Supplements 62. Drug Interactions Appendix I. Key Words for Key Drugs Appendix II. Examination 1 Appendix III. Examination 2 Appendix IV. Strategies for Improving Test Performance Index